Full-time: Boston United 1 Harrogate Town 2
Boston United turned in an abject display as they were deservedly beaten at home by Harrogate Town.
Chibuzor Chilaka's brace condemned the Pilgrims to their first home defeat under new manager Graham Drury.
Chilaka struck first after 20 minutes, forcing the ball home after Dan Haystead failed to hold Danny Forrest's stinging drive.
Boston rallied briefly at the start of the second half, but fell further behind when Chilaka steered home a right-wing cross.
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The Pilgrims' night went from bad to worse when substitute Charley Sanders was shown a straight red card after the referee deemed he had elbowed Harrogate's Shane Killock.
Marc Newsham pulled a goal back in the 90th minute, his 23rd of the season, but it was too little too late.
Pilgrims: Haystead, Silk, Watt, Ward, Jelleyman, J Smith (Sanders 69), Milnes (Stainfield 88), Ross, Fairclough (Jones 50), Weir-Daley, Newsham.
Subs not used: Reed, Drury (gk).